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Epidemiological analysis of respiratory viral etiology for influenza-like illness during 2010 in Zhuhai, China

BACKGROUND: Influenza-like illnesses (ILI), a subset of acute respiratory infections (ARI), are a significant source of morbidity and mortality worldwide. ILI can be caused by numerous pathogens, however; there is limited information on the etiology and epidemiology of ILI in China. METHODS: We perf...

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Autores principales: Li, Hongxia, Wei, Quande, Tan, Aijun, Wang, Leyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655035/
https://www.ncbi.nlm.nih.gov/pubmed/23651577
http://dx.doi.org/10.1186/1743-422X-10-143
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author Li, Hongxia
Wei, Quande
Tan, Aijun
Wang, Leyi
author_facet Li, Hongxia
Wei, Quande
Tan, Aijun
Wang, Leyi
author_sort Li, Hongxia
collection PubMed
description BACKGROUND: Influenza-like illnesses (ILI), a subset of acute respiratory infections (ARI), are a significant source of morbidity and mortality worldwide. ILI can be caused by numerous pathogens, however; there is limited information on the etiology and epidemiology of ILI in China. METHODS: We performed a one-year surveillance study (2010) of viral etiology causing ILI and investigated the influence of climate on outbreaks of ILI attributed to viruses at the Outpatient Department of Zhuhai Municipal People’s Hospital in Zhuhai, China. RESULTS: Of the 337,272 outpatients who sought attention in the Outpatient Department of Zhuhai Municipal People’s Hospital in 2010, 3,747 (1.11%) presented with ILI. Of these patients presenting with ILI, 24.66% (924/3,747) had available samples and were enrolled in this study. At least one respiratory virus was identified in 411 patients (44.48%) and 42 (4.55%) were co-infected with two viruses. In patients co-infected with two viruses, respiratory syncytial virus (RSV) was detected in 50% (21/42). Among common viral pathogens detected, significant differences in age distributions were observed in seasonal influenza virus A (sFulA, H3N2) and B (sFluB), pandemic H1N1 2009 influenza viruses (H1N1pdm09), RSV, and adenovirus (ADV). Infections with sFluA (H3N2), sFluB, RSV, and human metapneumovirus (HMPV) had characteristic seasonal patterns. The incidences of sFluA (H3N2), ADV, and RSV correlated with air temperature. Alternatively, the incidence of sFluB correlated with relative air humidity. CONCLUSIONS: These results demonstrate that a wide range of respiratory viral pathogens are circulating in Zhuhai city. This information needs to be considered by clinicians when treating patients presenting with ILI.
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spelling pubmed-36550352013-05-16 Epidemiological analysis of respiratory viral etiology for influenza-like illness during 2010 in Zhuhai, China Li, Hongxia Wei, Quande Tan, Aijun Wang, Leyi Virol J Research BACKGROUND: Influenza-like illnesses (ILI), a subset of acute respiratory infections (ARI), are a significant source of morbidity and mortality worldwide. ILI can be caused by numerous pathogens, however; there is limited information on the etiology and epidemiology of ILI in China. METHODS: We performed a one-year surveillance study (2010) of viral etiology causing ILI and investigated the influence of climate on outbreaks of ILI attributed to viruses at the Outpatient Department of Zhuhai Municipal People’s Hospital in Zhuhai, China. RESULTS: Of the 337,272 outpatients who sought attention in the Outpatient Department of Zhuhai Municipal People’s Hospital in 2010, 3,747 (1.11%) presented with ILI. Of these patients presenting with ILI, 24.66% (924/3,747) had available samples and were enrolled in this study. At least one respiratory virus was identified in 411 patients (44.48%) and 42 (4.55%) were co-infected with two viruses. In patients co-infected with two viruses, respiratory syncytial virus (RSV) was detected in 50% (21/42). Among common viral pathogens detected, significant differences in age distributions were observed in seasonal influenza virus A (sFulA, H3N2) and B (sFluB), pandemic H1N1 2009 influenza viruses (H1N1pdm09), RSV, and adenovirus (ADV). Infections with sFluA (H3N2), sFluB, RSV, and human metapneumovirus (HMPV) had characteristic seasonal patterns. The incidences of sFluA (H3N2), ADV, and RSV correlated with air temperature. Alternatively, the incidence of sFluB correlated with relative air humidity. CONCLUSIONS: These results demonstrate that a wide range of respiratory viral pathogens are circulating in Zhuhai city. This information needs to be considered by clinicians when treating patients presenting with ILI. BioMed Central 2013-05-07 /pmc/articles/PMC3655035/ /pubmed/23651577 http://dx.doi.org/10.1186/1743-422X-10-143 Text en Copyright © 2013 Li et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Li, Hongxia
Wei, Quande
Tan, Aijun
Wang, Leyi
Epidemiological analysis of respiratory viral etiology for influenza-like illness during 2010 in Zhuhai, China
title Epidemiological analysis of respiratory viral etiology for influenza-like illness during 2010 in Zhuhai, China
title_full Epidemiological analysis of respiratory viral etiology for influenza-like illness during 2010 in Zhuhai, China
title_fullStr Epidemiological analysis of respiratory viral etiology for influenza-like illness during 2010 in Zhuhai, China
title_full_unstemmed Epidemiological analysis of respiratory viral etiology for influenza-like illness during 2010 in Zhuhai, China
title_short Epidemiological analysis of respiratory viral etiology for influenza-like illness during 2010 in Zhuhai, China
title_sort epidemiological analysis of respiratory viral etiology for influenza-like illness during 2010 in zhuhai, china
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655035/
https://www.ncbi.nlm.nih.gov/pubmed/23651577
http://dx.doi.org/10.1186/1743-422X-10-143
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