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Reducing Uncertainty in Within-Host Parameter Estimates of Influenza Infection by Measuring Both Infectious and Total Viral Load

For in vivo studies of influenza dynamics where within-host measurements are fit with a mathematical model, infectivity assays (e.g. 50% tissue culture infectious dose; TCID(50)) are often used to estimate the infectious virion concentration over time. Less frequently, measurements of the total (inf...

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Detalles Bibliográficos
Autores principales:	Petrie, Stephen M., Guarnaccia, Teagan, Laurie, Karen L., Hurt, Aeron C., McVernon, Jodie, McCaw, James M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655064/ https://www.ncbi.nlm.nih.gov/pubmed/23691157 http://dx.doi.org/10.1371/journal.pone.0064098

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