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Identifying disruptors of male germ cell development by small molecule screening in ex vivo gonad cultures

BACKGROUND: Germ cell development involves formation of the spermatogenic or oogenic lineages from the bipotential primordial germ cells. Signaling mechanisms in the fetal testis and ovary determine whether germ cells enter the male or female developmental pathway, respectively. These signaling proc...

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Detalles Bibliográficos
Autores principales:	Wakeling, Stephanie I, Miles, Denise C, Western, Patrick S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Technical Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655070/ https://www.ncbi.nlm.nih.gov/pubmed/23631647 http://dx.doi.org/10.1186/1756-0500-6-168

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