Genome-Wide Transcriptional Reorganization Associated with Senescence-to-Immortality Switch during Human Hepatocellular Carcinogenesis

Senescence is a permanent proliferation arrest in response to cell stress such as DNA damage. It contributes strongly to tissue aging and serves as a major barrier against tumor development. Most tumor cells are believed to bypass the senescence barrier (become “immortal”) by inactivating growth con...

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Detalles Bibliográficos
Autores principales: Yildiz, Gokhan, Arslan-Ergul, Ayca, Bagislar, Sevgi, Konu, Ozlen, Yuzugullu, Haluk, Gursoy-Yuzugullu, Ozge, Ozturk, Nuri, Ozen, Cigdem, Ozdag, Hilal, Erdal, Esra, Karademir, Sedat, Sagol, Ozgul, Mizrak, Dilsa, Bozkaya, Hakan, Ilk, Hakki Gokhan, Ilk, Ozlem, Bilen, Biter, Cetin-Atalay, Rengul, Akar, Nejat, Ozturk, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655073/
https://www.ncbi.nlm.nih.gov/pubmed/23691139
http://dx.doi.org/10.1371/journal.pone.0064016

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