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The Positive Inotropic Effect of Pyruvate Involves an Increase in Myofilament Calcium Sensitivity

Pyruvate is a metabolic fuel that is a potent inotropic agent. Despite its unique inotropic and antioxidant properties, the molecular mechanism of its inotropic mechanism is still largely unknown. To examine the inotropic effect of pyruvate in parallel with intracellular calcium handling under near...

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Detalles Bibliográficos
Autores principales:	Torres, Carlos A. A., Varian, Kenneth D., Canan, Cynthia H., Davis, Jonathan P., Janssen, Paul M. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655183/ https://www.ncbi.nlm.nih.gov/pubmed/23691074 http://dx.doi.org/10.1371/journal.pone.0063608

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