Ubiquitination of HLA-DO by MARCH family E3 ligases

HLA-DO (DO) is a nonclassical MHC class II (MHCII) molecule that negatively regulates the ability of HLA-DM to catalyse the removal of invariant chain-derived CLIP peptides from classical MHCII molecules. Here, we show that DO is posttranslationally modified by ubiquitination. The location of the mo...

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Detalles Bibliográficos
Autores principales: Jahnke, Martin, Trowsdale, John, Kelly, Adrian P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Antigen Processing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655539/
https://www.ncbi.nlm.nih.gov/pubmed/23400868
http://dx.doi.org/10.1002/eji.201243043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655539/
https://www.ncbi.nlm.nih.gov/pubmed/23400868
http://dx.doi.org/10.1002/eji.201243043

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