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Haptoglobin Genotype-Dependent Anti-Inflammatory Signaling in CD163(+) Macrophages

Intraplaque hemorrhage causes adaptive remodelling of macrophages towards a protective phenotype specialized towards handling iron and lipid overload, denoted Mhem. The Mhem phenotype expresses elevated levels of hemoglobin (Hb) scavenger receptor, CD163, capable of endocytosing pro-oxidant free Hb...

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Detalles Bibliográficos
Autores principales:	Landis, R. Clive, Philippidis, Pandelis, Domin, Jan, Boyle, Joseph J., Haskard, Dorian O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655560/ https://www.ncbi.nlm.nih.gov/pubmed/23710416 http://dx.doi.org/10.1155/2013/980327

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