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Modulation of Brain Electroencephalography Oscillations by Electroacupuncture in a Rat Model of Postincisional Pain

The present study aimed to investigate how ongoing brain rhythmical oscillations changed during the postoperative pain and whether electroacupuncture (EA) regulated these brain oscillations when it relieved pain. We established a postincisional pain model of rats with plantar incision to mimic the c...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Li, Xuezhu, Li, Duan, Li, Xiao-Li, Han, Ji-Sheng, Wan, You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655616/
https://www.ncbi.nlm.nih.gov/pubmed/23710210
http://dx.doi.org/10.1155/2013/160357
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author Wang, Jing
Wang, Jing
Li, Xuezhu
Li, Duan
Li, Xiao-Li
Han, Ji-Sheng
Wan, You
author_facet Wang, Jing
Wang, Jing
Li, Xuezhu
Li, Duan
Li, Xiao-Li
Han, Ji-Sheng
Wan, You
author_sort Wang, Jing
collection PubMed
description The present study aimed to investigate how ongoing brain rhythmical oscillations changed during the postoperative pain and whether electroacupuncture (EA) regulated these brain oscillations when it relieved pain. We established a postincisional pain model of rats with plantar incision to mimic the clinical pathological pain state, tested the analgesic effects of EA, and recorded electroencephalography (EEG) activities before and after the EA application. By analysis of power spectrum and bicoherence of EEG, we found that in rats with postincisional pain, ongoing activities at the delta-frequency band decreased, while activities at theta-, alpha-, and beta-frequency bands increased. EA treatment on these postincisional pain rats decreased the power at high-frequency bands especially at the beta-frequency band and reversed the enhancement of the cross-frequency coupling strength between the beta band and low-frequency bands. After searching for the PubMed, our study is the first time to describe that brain oscillations are correlated with the processing of spontaneous pain information in postincisional pain model of rats, and EA could regulate these brain rhythmical frequency oscillations, including the power and cross-frequency couplings.
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spelling pubmed-36556162013-05-24 Modulation of Brain Electroencephalography Oscillations by Electroacupuncture in a Rat Model of Postincisional Pain Wang, Jing Wang, Jing Li, Xuezhu Li, Duan Li, Xiao-Li Han, Ji-Sheng Wan, You Evid Based Complement Alternat Med Research Article The present study aimed to investigate how ongoing brain rhythmical oscillations changed during the postoperative pain and whether electroacupuncture (EA) regulated these brain oscillations when it relieved pain. We established a postincisional pain model of rats with plantar incision to mimic the clinical pathological pain state, tested the analgesic effects of EA, and recorded electroencephalography (EEG) activities before and after the EA application. By analysis of power spectrum and bicoherence of EEG, we found that in rats with postincisional pain, ongoing activities at the delta-frequency band decreased, while activities at theta-, alpha-, and beta-frequency bands increased. EA treatment on these postincisional pain rats decreased the power at high-frequency bands especially at the beta-frequency band and reversed the enhancement of the cross-frequency coupling strength between the beta band and low-frequency bands. After searching for the PubMed, our study is the first time to describe that brain oscillations are correlated with the processing of spontaneous pain information in postincisional pain model of rats, and EA could regulate these brain rhythmical frequency oscillations, including the power and cross-frequency couplings. Hindawi Publishing Corporation 2013 2013-04-28 /pmc/articles/PMC3655616/ /pubmed/23710210 http://dx.doi.org/10.1155/2013/160357 Text en Copyright © 2013 Jing Wang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wang, Jing
Wang, Jing
Li, Xuezhu
Li, Duan
Li, Xiao-Li
Han, Ji-Sheng
Wan, You
Modulation of Brain Electroencephalography Oscillations by Electroacupuncture in a Rat Model of Postincisional Pain
title Modulation of Brain Electroencephalography Oscillations by Electroacupuncture in a Rat Model of Postincisional Pain
title_full Modulation of Brain Electroencephalography Oscillations by Electroacupuncture in a Rat Model of Postincisional Pain
title_fullStr Modulation of Brain Electroencephalography Oscillations by Electroacupuncture in a Rat Model of Postincisional Pain
title_full_unstemmed Modulation of Brain Electroencephalography Oscillations by Electroacupuncture in a Rat Model of Postincisional Pain
title_short Modulation of Brain Electroencephalography Oscillations by Electroacupuncture in a Rat Model of Postincisional Pain
title_sort modulation of brain electroencephalography oscillations by electroacupuncture in a rat model of postincisional pain
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655616/
https://www.ncbi.nlm.nih.gov/pubmed/23710210
http://dx.doi.org/10.1155/2013/160357
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