TGFβ1 microenvironment determines dendritic cell development

We have recently described two types of Langerhans cells (LCs), which develop via separate pathways in steady-state conditions and during inflammation. Here, we propose that these two types of LCs differ in their requirement for transforming growth factor β1 (TGFβ1), and we discuss how TGFβ1 impacts...

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Detalles Bibliográficos
Autores principales: Seré, Kristin, Felker, Piritta, Hieronymus, Thomas, Zenke, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655738/
https://www.ncbi.nlm.nih.gov/pubmed/23687620
http://dx.doi.org/10.4161/onci.23083
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author Seré, Kristin
Felker, Piritta
Hieronymus, Thomas
Zenke, Martin
author_facet Seré, Kristin
Felker, Piritta
Hieronymus, Thomas
Zenke, Martin
author_sort Seré, Kristin
collection PubMed
description We have recently described two types of Langerhans cells (LCs), which develop via separate pathways in steady-state conditions and during inflammation. Here, we propose that these two types of LCs differ in their requirement for transforming growth factor β1 (TGFβ1), and we discuss how TGFβ1 impacts on the development of other dendritic cell subtypes.
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spelling pubmed-36557382013-05-17 TGFβ1 microenvironment determines dendritic cell development Seré, Kristin Felker, Piritta Hieronymus, Thomas Zenke, Martin Oncoimmunology Author's View We have recently described two types of Langerhans cells (LCs), which develop via separate pathways in steady-state conditions and during inflammation. Here, we propose that these two types of LCs differ in their requirement for transforming growth factor β1 (TGFβ1), and we discuss how TGFβ1 impacts on the development of other dendritic cell subtypes. Landes Bioscience 2013-03-01 2013-03-01 /pmc/articles/PMC3655738/ /pubmed/23687620 http://dx.doi.org/10.4161/onci.23083 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Seré, Kristin
Felker, Piritta
Hieronymus, Thomas
Zenke, Martin
TGFβ1 microenvironment determines dendritic cell development
title TGFβ1 microenvironment determines dendritic cell development
title_full TGFβ1 microenvironment determines dendritic cell development
title_fullStr TGFβ1 microenvironment determines dendritic cell development
title_full_unstemmed TGFβ1 microenvironment determines dendritic cell development
title_short TGFβ1 microenvironment determines dendritic cell development
title_sort tgfβ1 microenvironment determines dendritic cell development
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655738/
https://www.ncbi.nlm.nih.gov/pubmed/23687620
http://dx.doi.org/10.4161/onci.23083
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AT hieronymusthomas tgfb1microenvironmentdeterminesdendriticcelldevelopment
AT zenkemartin tgfb1microenvironmentdeterminesdendriticcelldevelopment

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