Kinetic Model of Nav1.5 Channel Provides a Subtle Insight into Slow Inactivation Associated Excitability in Cardiac Cells

Voltage-gated sodium channel Nav1.5 has been linked to the cardiac cell excitability and a variety of arrhythmic syndromes including long QT, Brugada, and conduction abnormalities. Nav1.5 exhibits a slow inactivation, corresponding to a duration-dependent bi-exponential recovery, which is often asso...

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Detalles Bibliográficos
Autores principales: Zhang, Zheng, Zhao, Zhiwen, Liu, Yongfeng, Wang, Wei, Wu, Ying, Ding, Jiuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655986/
https://www.ncbi.nlm.nih.gov/pubmed/23696876
http://dx.doi.org/10.1371/journal.pone.0064286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655986/
https://www.ncbi.nlm.nih.gov/pubmed/23696876
http://dx.doi.org/10.1371/journal.pone.0064286

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