Three-Dimensional Collagen I Promotes Gemcitabine Resistance In Vitro in Pancreatic Cancer Cells through HMGA2-Dependent Histone Acetyltransferase Expression

Pancreatic ductal adenocarcinoma (PDAC) is associated with a pronounced collagen-rich stromal reaction that has been shown to contribute to chemo-resistance. We have previously shown that PDAC cells are resistant to gemcitabine chemotherapy in the collagen microenvironment because of increased expre...

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Detalles Bibliográficos
Autores principales: Dangi-Garimella, Surabhi, Sahai, Vaibhav, Ebine, Kazumi, Kumar, Krishan, Munshi, Hidayatullah G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655998/
https://www.ncbi.nlm.nih.gov/pubmed/23696899
http://dx.doi.org/10.1371/journal.pone.0064566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655998/
https://www.ncbi.nlm.nih.gov/pubmed/23696899
http://dx.doi.org/10.1371/journal.pone.0064566

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