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Intravenous Immunglobulin Binds Beta Amyloid and Modifies Its Aggregation, Neurotoxicity and Microglial Phagocytosis In Vitro

Intravenous Immunoglobulin (IVIG) has been proposed as a potential therapeutic for Alzheimer's disease (AD) and its efficacy is currently being tested in mild-to-moderate AD. Earlier studies reported the presence of anti-amyloid beta (Aβ) antibodies in IVIG. These observations led to clinical s...

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Detalles Bibliográficos
Autores principales: Cattepoel, Susann, Schaub, Alexander, Ender, Miriam, Gaida, Annette, Kropf, Alain, Guggisberg, Ursula, Nolte, Marc W., Fabri, Louis, Adlard, Paul A., Finkelstein, David I., Bolli, Reinhard, Miescher, Sylvia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656042/
https://www.ncbi.nlm.nih.gov/pubmed/23696796
http://dx.doi.org/10.1371/journal.pone.0063162