Tumor Derived Mutations of Protein Tyrosine Phosphatase Receptor Type K Affect Its Function and Alter Sensitivity to Chemotherapeutics in Glioma

Poor prognosis and resistance to therapy in malignant gliomas is mainly due to the highly dispersive nature of glioma cells. This dispersive characteristic results from genetic alterations in key regulators of cell migration and diffusion. A better understanding of these regulatory signals holds pro...

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Detalles Bibliográficos
Autores principales: Agarwal, Supreet, Al-Keilani, Maha S., Alqudah, Mohammad A. Y., Sibenaller, Zita A., Ryken, Timothy C., Assem, Mahfoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656086/
https://www.ncbi.nlm.nih.gov/pubmed/23696788
http://dx.doi.org/10.1371/journal.pone.0062852

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