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Structural Basis of HCV Neutralization by Human Monoclonal Antibodies Resistant to Viral Neutralization Escape

The high mutation rate of hepatitis C virus allows it to rapidly evade the humoral immune response. However, certain epitopes in the envelope glycoproteins cannot vary without compromising virus viability. Antibodies targeting these epitopes are resistant to viral escape from neutralization and unde...

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Detalles Bibliográficos
Autores principales:	Krey, Thomas, Meola, Annalisa, Keck, Zhen-yong, Damier-Piolle, Laurence, Foung, Steven K. H., Rey, Felix A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656090/ https://www.ncbi.nlm.nih.gov/pubmed/23696737 http://dx.doi.org/10.1371/journal.ppat.1003364

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