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Identification of Fibroblast Growth Factor Receptor 3 (FGFR3) as a Protein Receptor for Botulinum Neurotoxin Serotype A (BoNT/A)

Botulinum neurotoxin serotype A (BoNT/A) causes transient muscle paralysis by entering motor nerve terminals (MNTs) where it cleaves the SNARE protein Synaptosomal-associated protein 25 (SNAP25(206)) to yield SNAP25(197). Cleavage of SNAP25 results in blockage of synaptic vesicle fusion and inhibiti...

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Detalles Bibliográficos
Autores principales:	Jacky, Birgitte P. S., Garay, Patton E., Dupuy, Jérôme, Nelson, Jeremy B., Cai, Brian, Molina, Yanira, Wang, Joanne, Steward, Lance E., Broide, Ron S., Francis, Joseph, Aoki, K. Roger, Stevens, Raymond C., Fernández-Salas, Ester
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656097/ https://www.ncbi.nlm.nih.gov/pubmed/23696738 http://dx.doi.org/10.1371/journal.ppat.1003369

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