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Quantifying the Molecular Origins of Opposite Solvent Effects on Protein-Protein Interactions

Although the nature of solvent-protein interactions is generally weak and non-specific, addition of cosolvents such as denaturants and osmolytes strengthens protein-protein interactions for some proteins, whereas it weakens protein-protein interactions for others. This is exemplified by the puzzling...

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Detalles Bibliográficos
Autores principales: Vagenende, Vincent, Han, Alvin X., Pek, Han B., Loo, Bernard L. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656110/
https://www.ncbi.nlm.nih.gov/pubmed/23696727
http://dx.doi.org/10.1371/journal.pcbi.1003072

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