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Abortive Lytic Reactivation of KSHV in CBF1/CSL Deficient Human B Cell Lines
Since Kaposi's sarcoma associated herpesvirus (KSHV) establishes a persistent infection in human B cells, B cells are a critical compartment for viral pathogenesis. RTA, the replication and transcription activator of KSHV, can either directly bind to DNA or use cellular DNA binding factors incl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656114/ https://www.ncbi.nlm.nih.gov/pubmed/23696732 http://dx.doi.org/10.1371/journal.ppat.1003336 |