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Abortive Lytic Reactivation of KSHV in CBF1/CSL Deficient Human B Cell Lines

Since Kaposi's sarcoma associated herpesvirus (KSHV) establishes a persistent infection in human B cells, B cells are a critical compartment for viral pathogenesis. RTA, the replication and transcription activator of KSHV, can either directly bind to DNA or use cellular DNA binding factors incl...

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Detalles Bibliográficos
Autores principales:	Scholz, Barbara A., Harth-Hertle, Marie L., Malterer, Georg, Haas, Juergen, Ellwart, Joachim, Schulz, Thomas F., Kempkes, Bettina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656114/ https://www.ncbi.nlm.nih.gov/pubmed/23696732 http://dx.doi.org/10.1371/journal.ppat.1003336

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