Site-specific O-Glycosylation on the MUC2 Mucin Protein Inhibits Cleavage by the Porphyromonas gingivalis Secreted Cysteine Protease (RgpB)

The colonic epithelial surface is protected by an inner mucus layer that the commensal microflora cannot penetrate. We previously demonstrated that Entamoeba histolytica secretes a protease capable of dissolving this layer that is required for parasite penetration. Here, we asked whether there are b...

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Detalles Bibliográficos
Autores principales: van der Post, Sjoerd, Subramani, Durai B., Bäckström, Malin, Johansson, Malin E. V., Vester-Christensen, Malene B., Mandel, Ulla, Bennett, Eric P., Clausen, Henrik, Dahlén, Gunnar, Sroka, Aneta, Potempa, Jan, Hansson, Gunnar C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656315/
https://www.ncbi.nlm.nih.gov/pubmed/23546879
http://dx.doi.org/10.1074/jbc.M113.459479

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