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Converging Evidence for Epistasis between ANK3 and Potassium Channel Gene KCNQ2 in Bipolar Disorder

Genome-wide association studies (GWAS) have implicated ANK3 as a susceptibility gene for bipolar disorder (BP). We examined whether epistasis with ANK3 may contribute to the “missing heritability” in BP. We first identified via the STRING database 14 genes encoding proteins with prior biological evi...

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Detalles Bibliográficos
Autores principales:	Judy, Jennifer Toolan, Seifuddin, Fayaz, Pirooznia, Mehdi, Mahon, Pamela Belmonte, Jancic, Dubravka, Goes, Fernando S., Schulze, Thomas, Cichon, Sven, Noethen, Markus, Rietschel, Marcella, DePaulo, J. Raymond, Potash, James B., Zandi, Peter P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656345/ https://www.ncbi.nlm.nih.gov/pubmed/23730306 http://dx.doi.org/10.3389/fgene.2013.00087

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