Cargando…
New Strategies to Direct Therapeutic Targeting of PML to Treat Cancers
The tumor suppressor function of the promyelocytic leukemia (PML) protein was first identified as a result of its dysregulation in acute promyelocytic leukemia, however, its importance is now emerging far beyond hematological neoplasms, to an extensive range of malignancies, including solid tumors....
Autores principales: | Wolyniec, Kamil, Carney, Dennis A., Haupt, Sue, Haupt, Ygal |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656422/ https://www.ncbi.nlm.nih.gov/pubmed/23730625 http://dx.doi.org/10.3389/fonc.2013.00124 |
Ejemplares similares
-
Restoring PML tumor suppression to combat cancer
por: Wolyniec, Kamil, et al.
Publicado: (2012) -
Mutant p53 Drives Cancer by Subverting Multiple Tumor Suppression Pathways
por: Haupt, Sue, et al.
Publicado: (2016) -
p53 Calls upon CIA (Calcium Induced Apoptosis) to Counter Stress
por: Haupt, Sue, et al.
Publicado: (2015) -
Clinical Overview of MDM2/X-Targeted Therapies
por: Burgess, Andrew, et al.
Publicado: (2016) -
Regulation of Mutant p53 Protein Expression
por: Vijayakumaran, Reshma, et al.
Publicado: (2015)