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Conditional deletion of the human ortholog gene Dicer1 in Pax2-Cre expression domain impairs orofacial development

BACKGROUND: Orofacial clefts are common worldwide and result from insufficient growth and/or fusion during the genesis of the derivatives of the first pharyngeal arch and the frontonasal prominence. Recent studies in mice carrying conditional and tissue-specific deletions of the human ortholog Dicer...

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Detalles Bibliográficos
Autores principales: Barritt, Laura C., Miller, Joseph M., Scheetz, Laura R., Gardner, Kelsey, Pierce, Marsha L., Soukup, Garrett A., Rocha-Sanchez, Sonia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656520/
https://www.ncbi.nlm.nih.gov/pubmed/23716939
http://dx.doi.org/10.4103/0971-6866.107984