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Conditional deletion of the human ortholog gene Dicer1 in Pax2-Cre expression domain impairs orofacial development
BACKGROUND: Orofacial clefts are common worldwide and result from insufficient growth and/or fusion during the genesis of the derivatives of the first pharyngeal arch and the frontonasal prominence. Recent studies in mice carrying conditional and tissue-specific deletions of the human ortholog Dicer...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656520/ https://www.ncbi.nlm.nih.gov/pubmed/23716939 http://dx.doi.org/10.4103/0971-6866.107984 |