An uncommon case of an adult with del(5)(q) in acute lymphoblastic leukemia

Del(5)(q) is a common chromosomal abnormality with favourable prognosis in Myelodysplastic Syndrome (MDS) and Acute myeloid leukemia (AML). However, del(5)(q) is also seen rarely in Acute lymphoblastic leukemia (ALL) and its significance remains poorly understood. We present here, a case report of d...

Descripción completa

Detalles Bibliográficos
Autores principales: Venkataswamy, E., Nargund, Ashwini R., Prabhudesai, Shilpa, Patil, Geeta V., Chandra, Rao J., Veldore, Vidya H., Patil, Shekar, Verma, Amit, Sahoo, Rashmita, Ajaikumar, B. S., Prasannakumari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656527/
https://www.ncbi.nlm.nih.gov/pubmed/23716946
http://dx.doi.org/10.4103/0971-6866.108028
Descripción
Sumario:Del(5)(q) is a common chromosomal abnormality with favourable prognosis in Myelodysplastic Syndrome (MDS) and Acute myeloid leukemia (AML). However, del(5)(q) is also seen rarely in Acute lymphoblastic leukemia (ALL) and its significance remains poorly understood. We present here, a case report of diagnosis of an adult 75 year old patient of ALL with a cytogenetic abnormality of del(5)(q32). His clinical features, morphology and immunophenotyping findings were suggestive of T-ALL. Relevant literature has been reviewed and discussed.

Ejemplares similares