An uncommon case of an adult with del(5)(q) in acute lymphoblastic leukemia

Del(5)(q) is a common chromosomal abnormality with favourable prognosis in Myelodysplastic Syndrome (MDS) and Acute myeloid leukemia (AML). However, del(5)(q) is also seen rarely in Acute lymphoblastic leukemia (ALL) and its significance remains poorly understood. We present here, a case report of d...

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Autores principales: Venkataswamy, E., Nargund, Ashwini R., Prabhudesai, Shilpa, Patil, Geeta V., Chandra, Rao J., Veldore, Vidya H., Patil, Shekar, Verma, Amit, Sahoo, Rashmita, Ajaikumar, B. S., Prasannakumari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656527/
https://www.ncbi.nlm.nih.gov/pubmed/23716946
http://dx.doi.org/10.4103/0971-6866.108028
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author Venkataswamy, E.
Nargund, Ashwini R.
Prabhudesai, Shilpa
Patil, Geeta V.
Chandra, Rao J.
Veldore, Vidya H.
Patil, Shekar
Verma, Amit
Sahoo, Rashmita
Ajaikumar, B. S.
Prasannakumari,
author_facet Venkataswamy, E.
Nargund, Ashwini R.
Prabhudesai, Shilpa
Patil, Geeta V.
Chandra, Rao J.
Veldore, Vidya H.
Patil, Shekar
Verma, Amit
Sahoo, Rashmita
Ajaikumar, B. S.
Prasannakumari,
author_sort Venkataswamy, E.
collection PubMed
description Del(5)(q) is a common chromosomal abnormality with favourable prognosis in Myelodysplastic Syndrome (MDS) and Acute myeloid leukemia (AML). However, del(5)(q) is also seen rarely in Acute lymphoblastic leukemia (ALL) and its significance remains poorly understood. We present here, a case report of diagnosis of an adult 75 year old patient of ALL with a cytogenetic abnormality of del(5)(q32). His clinical features, morphology and immunophenotyping findings were suggestive of T-ALL. Relevant literature has been reviewed and discussed.
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spelling pubmed-36565272013-05-28 An uncommon case of an adult with del(5)(q) in acute lymphoblastic leukemia Venkataswamy, E. Nargund, Ashwini R. Prabhudesai, Shilpa Patil, Geeta V. Chandra, Rao J. Veldore, Vidya H. Patil, Shekar Verma, Amit Sahoo, Rashmita Ajaikumar, B. S. Prasannakumari, Indian J Hum Genet Case Report Del(5)(q) is a common chromosomal abnormality with favourable prognosis in Myelodysplastic Syndrome (MDS) and Acute myeloid leukemia (AML). However, del(5)(q) is also seen rarely in Acute lymphoblastic leukemia (ALL) and its significance remains poorly understood. We present here, a case report of diagnosis of an adult 75 year old patient of ALL with a cytogenetic abnormality of del(5)(q32). His clinical features, morphology and immunophenotyping findings were suggestive of T-ALL. Relevant literature has been reviewed and discussed. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3656527/ /pubmed/23716946 http://dx.doi.org/10.4103/0971-6866.108028 Text en Copyright: © Indian Journal of Human Genetics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Venkataswamy, E.
Nargund, Ashwini R.
Prabhudesai, Shilpa
Patil, Geeta V.
Chandra, Rao J.
Veldore, Vidya H.
Patil, Shekar
Verma, Amit
Sahoo, Rashmita
Ajaikumar, B. S.
Prasannakumari,
An uncommon case of an adult with del(5)(q) in acute lymphoblastic leukemia
title An uncommon case of an adult with del(5)(q) in acute lymphoblastic leukemia
title_full An uncommon case of an adult with del(5)(q) in acute lymphoblastic leukemia
title_fullStr An uncommon case of an adult with del(5)(q) in acute lymphoblastic leukemia
title_full_unstemmed An uncommon case of an adult with del(5)(q) in acute lymphoblastic leukemia
title_short An uncommon case of an adult with del(5)(q) in acute lymphoblastic leukemia
title_sort uncommon case of an adult with del(5)(q) in acute lymphoblastic leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656527/
https://www.ncbi.nlm.nih.gov/pubmed/23716946
http://dx.doi.org/10.4103/0971-6866.108028
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