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Inferring Gene Function and Network Organization in Drosophila Signaling by Combined Analysis of Pleiotropy and Epistasis
High-throughput genetic interaction screens have enabled functional genomics on a network scale. Groups of cofunctional genes commonly exhibit similar interaction patterns across a large network, leading to novel functional inferences for a minority of previously uncharacterized genes within a group...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Genetics Society of America
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656728/ https://www.ncbi.nlm.nih.gov/pubmed/23550134 http://dx.doi.org/10.1534/g3.113.005710 |