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Enhanced immune response against HIV-1 induced by a heterologous DNA prime-adenovirus boost vaccination using mannosylated polyethyleneimine as DNA vaccine adjuvant

BACKGROUND: The heterologous deoxyribonucleic acid (DNA) prime-adenovirus (AdV) boost vaccination approach has been widely applied as a promising strategy against human immunodeficiency virus (HIV)-1. However, the problem of inefficient delivery and lack of specificity of DNA vaccine remains a major...

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Detalles Bibliográficos
Autores principales:	Li, Man, Jiang, Yuhong, Xu, Chaoqun, Zhang, Zhirong, Sun, Xun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656813/ https://www.ncbi.nlm.nih.gov/pubmed/23690682 http://dx.doi.org/10.2147/IJN.S43827

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