Enhancing the bioactivity of Poly(lactic-co-glycolic acid) scaffold with a nano-hydroxyapatite coating for the treatment of segmental bone defect in a rabbit model

PURPOSE: Poly(lactic-co-glycolic acid) (PLGA) is excellent as a scaffolding matrix due to feasibility of processing and tunable biodegradability, yet the virgin scaffolds lack osteoconduction and osteoinduction. In this study, nano-hydroxyapatite (nHA) was coated on the interior surfaces of PLGA sca...

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Detalles Bibliográficos
Autores principales: Wang, De-Xin, He, Yao, Bi, Long, Qu, Ze-Hua, Zou, Ji-Wei, Pan, Zhen, Fan, Jun-Jun, Chen, Liang, Dong, Xin, Liu, Xiang-Nan, Pei, Guo-Xian, Ding, Jian-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656818/
https://www.ncbi.nlm.nih.gov/pubmed/23690683
http://dx.doi.org/10.2147/IJN.S43706

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