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Expression of Bovine Cytosolic 5′-Nucleotidase (cN-II) in Yeast: Nucleotide Pools Disturbance and Its Consequences on Growth and Homologous Recombination

Cytosolic 5′-nucleotidase II is a widespread IMP hydrolyzing enzyme, essential for cell vitality, whose role in nucleotide metabolism and cell function is still to be exactly determined. Cytosolic 5′-nucleotidase overexpression and silencing have both been demonstrated to be toxic for mammalian cult...

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Detalles Bibliográficos
Autores principales: Allegrini, Simone, Filoni, Daniela Nicole, Galli, Alvaro, Collavoli, Anita, Pesi, Rossana, Camici, Marcella, Tozzi, Maria Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656857/
https://www.ncbi.nlm.nih.gov/pubmed/23691116
http://dx.doi.org/10.1371/journal.pone.0063914