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Expression of Bovine Cytosolic 5′-Nucleotidase (cN-II) in Yeast: Nucleotide Pools Disturbance and Its Consequences on Growth and Homologous Recombination
Cytosolic 5′-nucleotidase II is a widespread IMP hydrolyzing enzyme, essential for cell vitality, whose role in nucleotide metabolism and cell function is still to be exactly determined. Cytosolic 5′-nucleotidase overexpression and silencing have both been demonstrated to be toxic for mammalian cult...
Autores principales: | Allegrini, Simone, Filoni, Daniela Nicole, Galli, Alvaro, Collavoli, Anita, Pesi, Rossana, Camici, Marcella, Tozzi, Maria Grazia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656857/ https://www.ncbi.nlm.nih.gov/pubmed/23691116 http://dx.doi.org/10.1371/journal.pone.0063914 |
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