ABT-263 Enhances Sensitivity to Metformin and 2-Deoxyglucose in Pediatric Glioma by Promoting Apoptotic Cell Death

Pediatric high grade glioma is refractory to conventional multimodal treatment, highlighting a need to develop novel efficacious therapies. We investigated tumor metabolism as a potential therapeutic target in a panel of diverse pediatric glioma cell lines (SF188, KNS42, UW479 and RES186) using metf...

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Detalles Bibliográficos
Autores principales: Levesley, Jane, Steele, Lynette, Taylor, Claire, Sinha, Priyank, Lawler, Sean E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656874/
https://www.ncbi.nlm.nih.gov/pubmed/23691145
http://dx.doi.org/10.1371/journal.pone.0064051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656874/
https://www.ncbi.nlm.nih.gov/pubmed/23691145
http://dx.doi.org/10.1371/journal.pone.0064051

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