Directed DNA Shuffling of Retrovirus and Retrotransposon Integrase Protein Domains

Chimeric proteins are used to study protein domain functions and to recombine protein domains for novel or optimal functions. We used a library of chimeric integrase proteins to study DNA integration specificity. The library was constructed using a directed shuffling method that we adapted from fusi...

Descripción completa

Detalles Bibliográficos
Autores principales: Qi, Xiaojie, Vargas, Edwin, Larsen, Liza, Knapp, Whitney, Hatfield, G. Wesley, Lathrop, Richard, Sandmeyer, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656877/
https://www.ncbi.nlm.nih.gov/pubmed/23691126
http://dx.doi.org/10.1371/journal.pone.0063957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656877/
https://www.ncbi.nlm.nih.gov/pubmed/23691126
http://dx.doi.org/10.1371/journal.pone.0063957

Ejemplares similares