Novel Associations of VKORC1 Variants with Higher Acenocoumarol Requirements

BACKGROUND: Algorithms combining both clinical and genetic data have been developed to improve oral anticoagulant therapy. Three polymorphisms in two genes, VKORC1 and CYP2C9, are the main coumarin dose determinants and no additional polymorphisms of any relevant pharmacogenetic importance have been...

Descripción completa

Detalles Bibliográficos
Autores principales: Anton, Ana Isabel, Cerezo-Manchado, Juan J., Padilla, Jose, Perez-Andreu, Virginia, Corral, Javier, Vicente, Vicente, Roldan, Vanessa, Gonzalez-Conejero, Rocio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656883/
https://www.ncbi.nlm.nih.gov/pubmed/23691226
http://dx.doi.org/10.1371/journal.pone.0064469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656883/
https://www.ncbi.nlm.nih.gov/pubmed/23691226
http://dx.doi.org/10.1371/journal.pone.0064469

Ejemplares similares