Characterization and evaluation of an oral microemulsion containing the antitumor diterpenoid compound ent-11alpha-hydroxy-15-oxo-kaur-16-en-19-oic-acid

The objective of this study was to develop an oral microemulsion formulation of the antitumor diterpenoid agent, ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid (henceforth referred to as 5F), to enhance its bioavailability and evaluate its hepatotoxicity. Pseudoternary phase diagrams showed that the...

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Detalles Bibliográficos
Autores principales: Lu, Yingnian, Wu, Kefeng, Li, Li, He, Yuhui, Cui, Liao, Liang, Nianci, Mu, Bozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656903/
https://www.ncbi.nlm.nih.gov/pubmed/23690685
http://dx.doi.org/10.2147/IJN.S42002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656903/
https://www.ncbi.nlm.nih.gov/pubmed/23690685
http://dx.doi.org/10.2147/IJN.S42002

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