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Broadening of the T-Cell Repertoire to HIV-1 Gag p24 by Vaccination of HLA-A2/DR Transgenic Mice with Overlapping Peptides in the CAF05 Adjuvant

Induction of broad T-cell immune responses is regarded as critical for vaccines against the human immunodeficiency virus type 1 (HIV-1) which exhibit high diversity and, therefore, focus has been on inducing cytotoxic CD8 T-cell responses against the more conserved parts of the virus, such as the Ga...

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Detalles Bibliográficos
Autores principales:	Korsholm, Karen S., Karlsson, Ingrid, Tang, Sheila T., Brandt, Lea, Agger, Else Marie, Aagaard, Claus, Andersen, Peter, Fomsgaard, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656914/ https://www.ncbi.nlm.nih.gov/pubmed/23691069 http://dx.doi.org/10.1371/journal.pone.0063575

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