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Defining ELISpot cut-offs from unreplicated test and control wells
In the absence of replication of wells, empirical criteria for enzyme-linked immunospot (ELISpot) positivity use fixed differences or ratios between spot forming units (SFU) counts between test and control. We propose an alternative approach which first identifies the optimally variance-stabilizing...
Autores principales: | Alexander, Neal, Fox, Annette, Lien, Vu Thi Kim, Dong, Tao, Lee, Laurel Yong-Hwa, Le Khanh Hang, Nguyen, Mai, Le Quynh, Horby, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657161/ https://www.ncbi.nlm.nih.gov/pubmed/23500146 http://dx.doi.org/10.1016/j.jim.2013.02.014 |
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