High frequency of the expanded C9ORF72 hexanucleotide repeat in familial and sporadic Greek ALS patients

An intronic expansion of a hexanucleotide GGGGCC repeat in the C9ORF72 gene has recently been shown to be an important cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) in familial and sporadic cases. The frequency has only been defined in a small number of populations w...

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Detalles Bibliográficos
Autores principales: Mok, Kin Y., Koutsis, Georgios, Schottlaender, Lucia V., Polke, James, Panas, Marios, Houlden, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Genetic Reports Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657168/
https://www.ncbi.nlm.nih.gov/pubmed/22445326
http://dx.doi.org/10.1016/j.neurobiolaging.2012.02.021

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