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Potentiation of sensory responses in ventrobasal thalamus in vivo via selective modulation of mGlu1 receptors with a positive allosteric modulator

Metabotropic glutamate subtype 1 (mGlu1) receptor is thought to play a role in synaptic responses in thalamic relay nuclei. The aim of this study was to evaluate the positive allosteric modulator (PAM) Ro67-4853 as a tool to modulate thalamic mGlu1 receptors on single thalamic neurones in vivo. Ro67...

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Detalles Bibliográficos
Autores principales:	Salt, T.E., Jones, H.E., Andolina, I.M., Copeland, C.S., Clements, J.T.C., Knoflach, F., Sillito, A.M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pergamon Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657174/ https://www.ncbi.nlm.nih.gov/pubmed/22178704 http://dx.doi.org/10.1016/j.neuropharm.2011.11.015

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