Cargando…

The Role of EGFR/ERK/ELK-1 MAP Kinase Pathway in the Underlying Damage to Diabetic Rat Skin

BACKGROUND: Diabetes mellitus (DM) is a highly prevalent disease. Atrophy and spontaneous ulcers are the most common cutaneous manifestation of diabetic dermopathy (DD). Before spontaneous ulcers, we believe there is an underlying damage stage although the mechanism is unknown. AIMS: To explore the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ge, Xinhong, Shi, Zhiyun, Yu, Nan, Jiao, Yaning, Jin, Li, Zhang, Jianzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2013
Materias:	Basic Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657207/ https://www.ncbi.nlm.nih.gov/pubmed/23716797 http://dx.doi.org/10.4103/0019-5154.108035

Ejemplares similares

Mechanical strain promotes skin fibrosis through LRG-1 induction mediated by ELK1 and ERK signalling
por: Gao, Ya, et al.
Publicado: (2019)

The Complexity of the ERK/MAP-Kinase Pathway and the Treatment of Melanoma Skin Cancer
por: Wellbrock, Claudia, et al.
Publicado: (2016)

A-Kinase Anchor Protein 95 Is Involved in ERK1/2–Elk-1 Signal Transduction in Colon Cancer
por: Kong, Xiangyu, et al.
Publicado: (2023)

Basic fibroblast growth factor induces matrix metalloproteinase-13 via ERK MAP kinase-altered phosphorylation and sumoylation of Elk-1 in human adult articular chondrocytes
por: Im, Hee-Jeong, et al.
Publicado: (2009)

ERK Signaling Controls Innate-like CD8(+) T Cell Differentiation via the ELK4 (SAP-1) and ELK1 Transcription Factors
por: Maurice, Diane, et al.
Publicado: (2018)

Integrin-Mediated Adhesion Regulates ERK Nuclear Translocation and Phosphorylation of Elk-1
por: Aplin, Andrew E., et al.
Publicado: (2001)

MTBP inhibits the Erk1/2-Elk-1 signaling in hepatocellular carcinoma
por: Ranjan, Atul, et al.
Publicado: (2018)

NIMA related kinase 2 promotes gastric cancer cell proliferation via ERK/MAPK signaling
por: Fan, Wei-Dong, et al.
Publicado: (2019)

ELK3 modulates the antitumor efficacy of natural killer cells against triple negative breast cancer by regulating mitochondrial dynamics
por: Park, Joo Dong, et al.
Publicado: (2022)

Ca(2+)/calmodulin-dependent protein kinase II regulates colon cancer proliferation and migration via ERK1/2 and p38 pathways
por: Chen, Wei, et al.
Publicado: (2017)

Mitogen-induced recruitment of ERK and MSK to SRE promoter complexes by ternary complex factor Elk-1
por: Zhang, Hong-Mei, et al.
Publicado: (2008)

ERK phosphorylation of MED14 in promoter complexes during mitogen-induced gene activation by Elk-1
por: Galbraith, Matthew D., et al.
Publicado: (2013)

ERK1 and ERK2 Map Kinases: Specific Roles or Functional Redundancy?
por: Buscà, Roser, et al.
Publicado: (2016)

Moxibustion eases chronic inflammatory visceral pain through regulating MEK, ERK and CREB in rats
por: Li, Zhi-Yuan, et al.
Publicado: (2017)

Mapping Brucellosis Increases Relative to Elk Density Using Hierarchical Bayesian Models
por: Cross, Paul C., et al.
Publicado: (2010)

Protective effects of panax notoginseng saponin on dextran sulfate sodium-induced colitis in rats through phosphoinositide-3-kinase protein kinase B signaling pathway inhibition
por: Lu, Qing-Ge, et al.
Publicado: (2020)

Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2
por: Perander, Maria, et al.
Publicado: (2017)

Efficacy of brain radiotherapy plus EGFR-TKI for EGFR-mutated non-small cell lung cancer patients who develop brain metastasis
por: Wang, Wenxian, et al.
Publicado: (2018)

Nuclear Export of Map Kinase (ERK) Involves a Map Kinase Kinase (Mek-Dependent) Active Transport Mechanism
por: Adachi, Makoto, et al.
Publicado: (2000)

Pathological characterization of TgElk mice injected with brain homogenate from elk with chronic wasting disease
por: Jeon, Yong-Chul, et al.
Publicado: (2013)

Semen affects the biological behavior of HeLa cells by altering ERK signaling
por: Guo, Zhi-Qiang, et al.
Publicado: (2019)

Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A
por: Chao, Ting-Ting, et al.
Publicado: (2014)

Elk nadeel heeft zijn voordeel
por: Eenhoorn, Anneke
Publicado: (2020)

XRP44X, an Inhibitor of Ras/Erk Activation of the Transcription Factor Elk3, Inhibits Tumour Growth and Metastasis in Mice
por: Semenchenko, Kostyantyn, et al.
Publicado: (2016)

Case Report: Fading Elk Syndrome in a Herd of Captive Elk (Cervus elaphus) in the North American Midwest
por: Boggiatto, Paola M., et al.
Publicado: (2020)

The influence of sleep deprivation and obesity on DNA damage in female Zucker rats
por: Tenorio, Neuli M., et al.
Publicado: (2013)

Manuka honey protects middle-aged rats from oxidative damage
por: Jubri, Zakiah, et al.
Publicado: (2013)

Reabsorption of iron into acutely damaged rat liver: A role for ferritins
por: Malik, Ihtzaz Ahmed, et al.
Publicado: (2017)

Effects of water cooling on laser‐induced thermal damage in rat hepatectomy
por: Shan, Liyu, et al.
Publicado: (2022)

Aspirin-Induced Gastric Lesions Alters EGFR and PECAM-1 Immunoreactivity in Wistar Rats: Modulatory Action of Flavonoid Fraction of Musa Paradisiaca
por: Alese, Margaret Olutayo, et al.
Publicado: (2017)

Rosiglitazone protects against severe hemorrhagic shock-induced organ damage in rats
por: Yang, Fwu-Lin, et al.
Publicado: (2011)

Melatonin prevents oxidative stress, inflammatory activity, and DNA damage in cirrhotic rats
por: Colares, Josieli R, et al.
Publicado: (2022)

Alternatively spliced isoforms of the human elk-1 mRNA within the 5′ UTR: implications for ELK-1 expression
por: Araud, Tanguy, et al.
Publicado: (2007)

HPV-18 E7 Interacts with Elk-1 Leading to Elevation of the Transcriptional Activity of Elk-1 in Cervical Cancer
por: Go, Sung-Ho, et al.
Publicado: (2022)

A Quantitative Model of ERK MAP Kinase Phosphorylation in Crowded Media
por: Aoki, Kazuhiro, et al.
Publicado: (2013)

The Non-Classical MAP Kinase ERK3 Controls T Cell Activation
por: Marquis, Miriam, et al.
Publicado: (2014)

Black Elk speaks : being the life story of a holy man of the Oglala Sioux /
por: Neihardt, John G., 1881-1973
Publicado: (1988)

VEGF-Induced Expression of miR-17–92 Cluster in Endothelial Cells Is Mediated by ERK/ELK1 Activation and Regulates Angiogenesis
por: Chamorro-Jorganes, Aránzazu, et al.
Publicado: (2016)

c‐KIT‐ERK1/2 signaling activated ELK1 and upregulated carcinoembryonic antigen expression to promote colorectal cancer progression
por: Ma, Jian, et al.
Publicado: (2020)

NLK is required for Ras/ERK/SRF/ELK signaling to tune skeletal muscle development by phosphorylating SRF and antagonizing the SRF/MKL pathway
por: Li, Shang-Ze, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_emll8kn2j7d6tgtnne0g09s78r