Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections

Treatment of Scedosporium apiospermum central nervous system (CNS) infection typically consists of an azole in combination with surgical debridement. This approach requires prolonged treatment and carries a high associated mortality. We present two cases of the successful treatment of S. apiospermum...

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Detalles Bibliográficos
Autores principales: Henao-Martínez, Andrés F., Castillo-Mancilla, José R., Barron, Michelle A., Nichol, Aran Cunningham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657419/
https://www.ncbi.nlm.nih.gov/pubmed/23738164
http://dx.doi.org/10.1155/2013/589490
Descripción
Sumario:Treatment of Scedosporium apiospermum central nervous system (CNS) infection typically consists of an azole in combination with surgical debridement. This approach requires prolonged treatment and carries a high associated mortality. We present two cases of the successful treatment of S. apiospermum CNS infections with the combination of voriconazole and terbinafine.

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