Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections

Treatment of Scedosporium apiospermum central nervous system (CNS) infection typically consists of an azole in combination with surgical debridement. This approach requires prolonged treatment and carries a high associated mortality. We present two cases of the successful treatment of S. apiospermum...

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Autores principales: Henao-Martínez, Andrés F., Castillo-Mancilla, José R., Barron, Michelle A., Nichol, Aran Cunningham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657419/
https://www.ncbi.nlm.nih.gov/pubmed/23738164
http://dx.doi.org/10.1155/2013/589490
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author Henao-Martínez, Andrés F.
Castillo-Mancilla, José R.
Barron, Michelle A.
Nichol, Aran Cunningham
author_facet Henao-Martínez, Andrés F.
Castillo-Mancilla, José R.
Barron, Michelle A.
Nichol, Aran Cunningham
author_sort Henao-Martínez, Andrés F.
collection PubMed
description Treatment of Scedosporium apiospermum central nervous system (CNS) infection typically consists of an azole in combination with surgical debridement. This approach requires prolonged treatment and carries a high associated mortality. We present two cases of the successful treatment of S. apiospermum CNS infections with the combination of voriconazole and terbinafine.
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spelling pubmed-36574192013-06-04 Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections Henao-Martínez, Andrés F. Castillo-Mancilla, José R. Barron, Michelle A. Nichol, Aran Cunningham Case Rep Infect Dis Case Report Treatment of Scedosporium apiospermum central nervous system (CNS) infection typically consists of an azole in combination with surgical debridement. This approach requires prolonged treatment and carries a high associated mortality. We present two cases of the successful treatment of S. apiospermum CNS infections with the combination of voriconazole and terbinafine. Hindawi Publishing Corporation 2013 2013-04-29 /pmc/articles/PMC3657419/ /pubmed/23738164 http://dx.doi.org/10.1155/2013/589490 Text en Copyright © 2013 Andrés F. Henao-Martínez et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Henao-Martínez, Andrés F.
Castillo-Mancilla, José R.
Barron, Michelle A.
Nichol, Aran Cunningham
Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections
title Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections
title_full Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections
title_fullStr Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections
title_full_unstemmed Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections
title_short Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections
title_sort combination antifungal therapy in the treatment of scedosporium apiospermum central nervous system infections
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657419/
https://www.ncbi.nlm.nih.gov/pubmed/23738164
http://dx.doi.org/10.1155/2013/589490
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