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Effect of Lutein and Antioxidant Supplementation on VEGF Expression, MMP-2 Activity, and Ultrastructural Alterations in Apolipoprotein E-Deficient Mouse
Oxidative stress is involved in the pathogenesis of several diseases such as atherosclerosis and age-related macular degeneration (AMD). ApoE-deficient mice (apoE(−/−)) are a well-established model of genetic hypercholesterolemia and develop retinal alterations similar to those found in humans with...
Autores principales: | Fernández-Robredo, Patricia, Sádaba, Luis M., Salinas-Alamán, Angel, Recalde, Sergio, Rodríguez, José A., García-Layana, Alfredo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657460/ https://www.ncbi.nlm.nih.gov/pubmed/23738034 http://dx.doi.org/10.1155/2013/213505 |
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