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Genetic variability & chemotoxicity of 5-fluorouracil & cisplatin in head & neck cancer patients: a preliminary study

BACKGROUND & OBJECTIVES: The efficacy and toxicity of a given chemotherapy regimen varies widely among patients due to the inherited variability of genes that are involved in drug metabolism. There are several crucial enzymes identified involving metabolism of 5-fluorouracil (5-FU) and cisplatin...

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Detalles Bibliográficos
Autores principales:	Dhawan, Dipali, Panchal, Harsha, Shukla, Shilin, Padh, Harish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657875/ https://www.ncbi.nlm.nih.gov/pubmed/23481061

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