Evaluation of acrosome intactness status in male infertility in Mysore, South India

BACKGROUND AND OBJECTIVE: The objective of this study is to determine the status of acrosome intactness in different infertile conditions among men who have attended the Mediwave Fertility Research Center, Mysore, South India. MATERIALS AND METHODS: A total of 70 infertile and 20 control subjects were employed in the study. Infertile subjects were classified into different conditions according to the WHO protocol. The data obtained was statistically analyzed. RESULTS: In the present study, seven different infertile conditions were reported. For the acrosome intactness test, except oligospermia, all other conditions recorded a statistically significant value (P < 0.05) compared with the control group. CONCLUSIONS: The present study shows the decreased acrosomal enzyme activity in infertile males compared with fertile males. If diagnosed and treated earlier, it may help in the success of the in vitro fertilization technique.