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Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome
Fragile X syndrome, the most commonly known genetic cause of autism, is due to loss of the fragile X mental retardation protein, which regulates signal transduction at metabotropic glutamate receptor-5 in the brain. Fragile X mental retardation protein deletion in mice enhances metabotropic glutamat...
Autores principales: | Jung, Kwang-Mook, Sepers, Marja, Henstridge, Christopher M., Lassalle, Olivier, Neuhofer, Daniela, Martin, Henry, Ginger, Melanie, Frick, Andreas, DiPatrizio, Nicholas V., Mackie, Ken, Katona, Istvan, Piomelli, Daniele, Manzoni, Olivier J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657999/ https://www.ncbi.nlm.nih.gov/pubmed/23011134 http://dx.doi.org/10.1038/ncomms2045 |
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