Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B

Although heat-shock protein 70 (HSP70), an evolutionarily highly conserved molecular chaperone, is known to be post-translationally modified in various ways such as phosphorylation, ubiquitination and glycosylation, physiological significance of lysine methylation has never been elucidated. Here we...

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Detalles Bibliográficos
Autores principales: Cho, Hyun-Soo, Shimazu, Tadahiro, Toyokawa, Gouji, Daigo, Yataro, Maehara, Yoshihiko, Hayami, Shinya, Ito, Akihiro, Masuda, Ken, Ikawa, Noriko, Field, Helen I., Tsuchiya, Eiju, Ohnuma, Shin-ichi, Ponder, Bruce A.J., Yoshida, Minoru, Nakamura, Yusuke, Hamamoto, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658001/
https://www.ncbi.nlm.nih.gov/pubmed/22990868
http://dx.doi.org/10.1038/ncomms2074

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