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High-performance thin layer chromatography: A powerful analytical technique in pharmaceutical drug discovery

Analysis of pharmaceutical and natural compounds and newer drugs is commonly used in all the stages of drug discovery and development process. High-performance thin layer chromatography is one of the sophisticated instrumental techniques based on the full capabilities of thin layer chromatography. T...

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Detalles Bibliográficos
Autores principales: Attimarad, Mahesh, Ahmed, K. K. Mueen, Aldhubaib, Bandar E., Harsha, Sree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658041/
https://www.ncbi.nlm.nih.gov/pubmed/23781433
http://dx.doi.org/10.4103/2229-4708.84436
Descripción
Sumario:Analysis of pharmaceutical and natural compounds and newer drugs is commonly used in all the stages of drug discovery and development process. High-performance thin layer chromatography is one of the sophisticated instrumental techniques based on the full capabilities of thin layer chromatography. The advantages of automation, scanning, full optimization, selective detection principle, minimum sample preparation, hyphenation, and so on enable it to be a powerful analytical tool for chromatographic information of complex mixtures of pharmaceuticals, natural products, clinical samples, food stuffs, and so on.