Simultaneous determination of losartan, losartan acid and amlodipine in human plasma by LC-MS/MS and its application to a human pharmacokinetic study

INTRODUCTION: A simple, rapid and sensitive liquid chromatography-tandem mass spectrometric assay method has been developed and fully validated for simultaneous quantification of losartan and its active metabolite, losartan carboxylic acid, and amlodipine in human plasma. Irbesartan was used as an i...

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Detalles Bibliográficos
Autores principales: Karra, Vijaya Kumari, Pilli, Nageswara Rao, Inamadugu, Jaswanth Kumar, Rao, J. V. L. N. Seshagiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658069/
https://www.ncbi.nlm.nih.gov/pubmed/23781473
http://dx.doi.org/10.4103/2229-4708.97711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658069/
https://www.ncbi.nlm.nih.gov/pubmed/23781473
http://dx.doi.org/10.4103/2229-4708.97711

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