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Stability of temozolomide in solutions aimed for oral treatment prepared from a commercially available powder for infusion
BACKGROUND: Temozolomide (TMZ) is an alkylating agent with a broad spectrum of antitumor activity, including brain tumors in children. The oral use of TMZ is hampered by the lack of a suitable galenic formulation, since the capsules of TMZ (Temodal™) are large and difficult to swallow. A powder for...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658070/ https://www.ncbi.nlm.nih.gov/pubmed/23781469 http://dx.doi.org/10.4103/2229-4708.97700 |