Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

Associations between single nucleotide polymorphisms (SNPs) at 5p15 and multiple cancer types have been reported. We have previously shown evidence for a strong association between prostate cancer (PrCa) risk and rs2242652 at 5p15, intronic in the telomerase reverse transcriptase (TERT) gene that en...

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Detalles Bibliográficos
Autores principales: Kote-Jarai, Zsofia, Saunders, Edward J., Leongamornlert, Daniel A., Tymrakiewicz, Malgorzata, Dadaev, Tokhir, Jugurnauth-Little, Sarah, Ross-Adams, Helen, Al Olama, Ali Amin, Benlloch, Sara, Halim, Silvia, Russel, Roslin, Dunning, Alison M., Luccarini, Craig, Dennis, Joe, Neal, David E., Hamdy, Freddie C., Donovan, Jenny L., Muir, Ken, Giles, Graham G., Severi, Gianluca, Wiklund, Fredrik, Gronberg, Henrik, Haiman, Christopher A., Schumacher, Fredrick, Henderson, Brian E., Le Marchand, Loic, Lindstrom, Sara, Kraft, Peter, Hunter, David J., Gapstur, Susan, Chanock, Stephen, Berndt, Sonja I., Albanes, Demetrius, Andriole, Gerald, Schleutker, Johanna, Weischer, Maren, Canzian, Federico, Riboli, Elio, Key, Tim J., Travis, Ruth C., Campa, Daniele, Ingles, Sue A., John, Esther M., Hayes, Richard B., Pharoah, Paul, Khaw, Kay-Tee, Stanford, Janet L., Ostrander, Elaine A., Signorello, Lisa B., Thibodeau, Stephen N., Schaid, Dan, Maier, Christiane, Vogel, Walther, Kibel, Adam S., Cybulski, Cezary, Lubinski, Jan, Cannon-Albright, Lisa, Brenner, Hermann, Park, Jong Y., Kaneva, Radka, Batra, Jyotsna, Spurdle, Amanda, Clements, Judith A., Teixeira, Manuel R., Govindasami, Koveela, Guy, Michelle, Wilkinson, Rosemary A., Sawyer, Emma J., Morgan, Angela, Dicks, Ed, Baynes, Caroline, Conroy, Don, Bojesen, Stig E., Kaaks, Rudolf, Vincent, Daniel, Bacot, François, Tessier, Daniel C., Easton, Douglas F., Eeles, Rosalind A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Association Studies Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658165/
https://www.ncbi.nlm.nih.gov/pubmed/23535824
http://dx.doi.org/10.1093/hmg/ddt086

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